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Oncology Nursing Careers in Duarte and Irvine, California

Whether you're an experienced Oncology RN or looking to build your career in Oncology, you'll find exceptional opportunities at our comprehensive cancer care centers. New grads are also welcome!

Let’s have a conversation! Got questions? We’re here to help.

Medical Oncology • Hematology • Bone Marrow Transplant • Operating Room • Intensive Care Unit • Ambulatory

Why Choose Us?

We are a recognized leader at the forefront of research and innovation, so you can help make a real difference in the fight against cancer by delivering the cures of tomorrow to the people who need them today. We are Magnet-recognized, offer a great staff-to-patient ratio, excellent benefits, professional development programs, and a welcoming culture of inclusion.

Annette M Walker,
President
Orange County, CA

From Our Leadership

Nurses at the City of Hope are dedicated to, and passionate about, the provision of compassionate cancer and diabetes care. But we recognize that our professional nursing practice goes way beyond caring. As oncology nurses we are clinically excellent in one of the most complex nursing specialties. We utilize critical thinking, clinical judgment, and scientific inquiry to ensure both optimal care and patient/family outcomes.

With advanced nursing leadership development, a robust collaborative governance structure and focus on clinical innovation in surgical, inpatient and outpatient settings, nurses have the support to develop the practice they envision.

Susan Brown, SVP Patient Care Services, Chief Nursing Officer
Duarte, CA

Let’s have a conversation! Got questions? We’re here to help.

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Your Success Matters

Professional Development

We invest in your professional advancement through our clinical ladder program, national certification support programs, online learning platforms, and evidence-based practice resources.

Benefits & Wellness

We proudly offer comprehensive benefit packages to take care of you and your family including Health Plans, FSA/HSA, Life Insurance, Disability, EAP, HC Management Resources, Cancer Support Services and more!

Join a Top 10 Cancer Hospital

The expert clinicians in our cancer centers collaborate daily, delivering comprehensive, personalized treatments tailored to each patient’s individual needs. We are Magnet-recognized, offer a staff-to-patient ratio that allows you to focus on individualized care and are proud to be ranked among the Top 10 Cancer Hospitals in the nation.

City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix.

Awards & Recognition

  • 1st ANCC Magnet Designation® achieved 2021
  • Founding Member, National Comprehensive Cancer Network
  • Our National Cancer Center near Los Angeles has ranked eighth for Best Hospitals in the U.S. World News & Report 2023; 17th year in a row on the list.
  • Second ANCC PTAP with Distinction for Alan and Marlene Nurse Residency Program achieved 2023
  • 2022-2023: Over $130,000 in grants and donations received for Nursing
  • 93% BSN+, 38% certified nurses overall
  • 35+ clinical network sites
  • Orange County Lennar Foundation Cancer Center opened in August 2022
  • Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center.

City of Hope California

Our National Cancer Center, situated on 100+ acres in the city of Duarte, is located northeast of Los Angeles. The Orange County Lennar Foundation Cancer Center is located in the FivePoint Gateway community in Irvine, California. New hospital opening in 2025!

Voices of Our Valued Patients

Marcelo V., Kidney Cancer

"There is a superior level of cancer care at City of Hope Orange County.”

Sheree S., Breast Cancer

“Hope to God I never have cancer again, but the only place I'm coming is City of Hope.”

Bob S., Leukemia

“Through 11 weeks of inpatient care, the 24-hour attention I received from these amazing care professionals made all the difference.”